This dataset includes the full-size montage (.tiff) of the retinal pigment epithelium (RPE) cell mosaic for each of 10 participants studied in Granger et al, 2018. Individual regions of interest (ROIs) used for analysis in the study are also provided, including raw RPE fluorescence, automated RPE segmentation, corrected RPE segmentation, raw photoreceptor near-infrared reflectance, and marked cones. High resolution images were acquired in the living human eye using an adaptive optics scanning light ophthalmoscope modified to excite and collect lipofuscin autofluorescence and photoreceptor near-infrared reflectance. The table below provides participant phenotype information and the pixel scale factor and "center" coordinates used in the study. Information regarding data acquisition, processing, and analysis, is detailed in the publication. Participant Age (yr) Sex Axial Length (mm) Foveal Center Pixel Values (x,y) Scale Factor (µm/pixel) NOR062 23 F 23.85 (2176, 2756) 0.863 NOR064 25 F 24.12 (4769, 614) 0.872 NOR053 27 F 24.07 (6099, 808) 0.87 NOR065 27 F 24.28 (5536, 690) 0.878 NOR057 35 F 23.76 (4062, 935) 0.859 NOR063 35 M 23.25 (5302, 747) 0.841 NOR047 41 M 23.61 (5072, 792) 0.854 NOR073* 55 F 22.51 (4190, 424) 0.814 NOR011 62 F 25.52 (5109, 540) 0.923 NOR025 65 M 24.79 (4848, 368) 0.897 Eccentricity in degrees of visual field may be calculated for all participants using the scale factor of 333.913 pixels/degree. *OS eye. All other eyes OD Corrected RPE segmentation ROIs are only provided for those where graders could confidently determine cell boundaries. Marked cone photoreceptor ROIs were only created for ROIs where cone cells could be clearly identified or differentiated from rod photoreceptors. Additionally, cones were only marked in regions of the ROI where RPE cells were identified. ROI file names are prefixed with "N_", "T_", or "foveal_center_", representing "nasal", "temporal", or foveal center, respectively. Additional ROI prefixes "LL_", "UL_", "UR_", and "LR_" may exist and represent additional ROIs placed in "lower left", "upper left", "upper right" and "lower right" quadrants of the montage, respectively. ROIs are sequentially numbered following the prefix, corresponding to increasing eccentricity from the fovea.