T-cell repertoire characterization data are provided herein as a supplement to: High-Throughput Sequencing of the T-cell receptor beta chain gene distinguishes two subgroups of cutaneous T-cell lymphoma By Jie Wang, MD, Bryan Rea, MD, Paul Haun, MD, Ryan Emerson, PhD, Ilan Kirsch, MD, Adam Bagg, MD Included are the original data used for the analyses presented in the manuscript, 92 files in total. Samples are arranged according to subject number, diagnosis (reactive or CTCL), and sample type (skin or blood). There is a skin and blood sample for each subject. For example, 1 HUP12 React-Blood and 1 HUP13 React-Skin are the blood and skin samples from subject #1 who had reactive skin disease. Each file is a set of TCR sequencing data, one line per unique TCR observed in the dataset, with tab-separated columns of additional annotations. Relevant annotation columns: nucleotide - nucleotide sequence of the CDR3 region aminoAcid - Amino Acid translation of the CDR3 region count (templates) - Sequence read counts for this receptor frequencyCount (%) - Proportional abundance of this receptor in the dataset cdr3Length - length of the CDR3 region (in NT) vMaxResolved - The V gene segment used in this rearrangement