Differential avoidance of the odour of opposite sex mice receiving acute and repeated Lipopolysaccharide
Data files
Oct 24, 2025 version files 4.78 KB
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Preference_Data_(Proceedings_B).csv
3.08 KB
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README.md
1.70 KB
Abstract
This data set represents the odour preference ratios of four experimental groups (namely Group 1: "Female (Treated/Treated+Untreated)"; Group 2: "Female (Treated/Treated+Blank)"; Group 3: "Male (Treated/Treated+Untreated)"; Group 4: "Male (Treated/Treated+Blank)"). Each of these four groups contains odour preference data from 10 mice at both Day 1 and Day 7 and that mouses odour preference to the three conditions (0 ug/kg; 1 ug/kg; 25 ug/kg).
Dataset DOI: 10.5061/dryad.1jwstqk62
Description of the data and file structure
Here we considered the responses of both male and female mice to the odours of opposite sex individuals acutely (Day 1) and repeatedly (Day 7) treated with very low and low doses of LPS (1.0 and 25 μg/kg, respectively).
Odour preference ratio for an LPS treated male or female was calculated by dividing time spent in proximity of the LPS odour by the total time spent in proximity of both odours (i.e., [LPS treated (Day 1)]/[LPS treated (Day 1) + Untreated (Day 1)]. One sample t-tests were used to test whether the odour preferences differed from random (preference ratio of 0.5).
Files and variables
File: Preference_Data_(Proceedings_B).csv
Description: Odour Preference Data showing preference ratios of both male and female mice in a Y-Maze
Variables
- 0 ug/kg;1 ug/kg; 25 ug/kg are the doses of LPS that mice were treated with.
- ug/kg= microgram per kilogram
- Day 1 and Day 7: these were the days in which the mice were run through a Y-maze. Day 1, mice were exposed to odours of conspecifics that were treated with each respective dose of LPS for one day, while Day 7 was odours of mice treated with each respective dose of LPS at Day 7.
- Preference Ratios: calculated by dividing time spent in proximity of the LPS odour by the total time spent in proximity of both odours (i.e., [LPS treated (Day 1)]/[LPS treated (Day 1) + Untreated (Day 1)].
- There are no missing values
Code/software
Excel Version 16.95.3 is required