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Data from: Systematic evaluation of magnetic particle imaging quantification strategies in biologically relevant scenarios using anatomically correct 3D printed mouse phantoms

Valdés, Daniela P.1; Zammataro, Sarah N.1; Melnyk, Andrii1; Velazquez-Albino, Ambar C.1; Ali, Sk Rajab1; Rinaldi-Ramos, Carlos M.1

Published Jul 27, 2026 on Dryad. https://doi.org/10.5061/dryad.59zw3r2pz

Data files

Jul 27, 2026 version files 6.42 GB

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Abstract

This dataset contains images of a mouse phantom used to evaluate segmentation methods in magnetic particle imaging (MPI) under biomedically-relevant conditions. The dataset includes MPI images of a mouse phantom with 100 ugFe in the liver cavity and various test masses (ranging from 0 to 2.5 ugFe) in the brain, hind flank and lung regions of interest (ROI). The 2D and 3D MPI images are provided in .nrrd format and segmentations of the ROI signal in .seg.nrrd format. Data were obtained using MOMENTUM Magnetic Particle Imaging Scanner (Magnetic Insight) and a lab-made iron oxide tracer coated with nDPEG. The phantom models used for 3D printing (brain and lung ports + liver and hind flank cavities) are provided in STL format, as well as another model that contains brain, lung, liver and hind flank anatomical cavities. A registered computed tomography (CT) image of all phantom configurations is also provided. The dataset is organized into folders containing the imaging data (.nrrd), folders containing tabular data (.txt) plotted in the article and the phantom models (.stl). The imaging data consist of each dataset that was studied (brain, flank and lung) and folders with additional data such as the reference samples that were used to calibrate signal into iron mass. and the models. This dataset has broader relevance for advancing quantitative imaging techniques in MPI for magnetic nanoparticle biodistribution studies.