Data from: Molecular genetics of sex identification, breed ancestry and polydactyly in the Norwegian Lundehund breed
Data files
Apr 27, 2015 version files 16.84 MB
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Kropatsch et al 2015 Norwegian Lundehund Y mtDNA genetic data.xlsx
25.68 KB
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Lundehund1_information.txt
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Lundehund1.map
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Lundehund1.ped
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README_for_Lundehund1_information.txt
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README_for_Lundehund1.txt
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README_for_Lundehund1.txt
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Abstract
The Norwegian Lundehund breed of dog has undergone a severe loss of genetic diversity as a result of inbreeding and epizootics of canine distemper. As a consequence, the breed is extremely homogeneous and accurate sex identification is not always possible by standard screening of X-chromosomal loci. To improve our genetic understanding of the breed we genotyped 17 individuals using a genome-wide array of 170 000 single nucleotide polymorphisms (SNPs). Standard analyses based on expected homozygosity of X-chromosomal loci failed in assigning individuals to the correct sex, as determined initially by physical examination and confirmed with the Y-chromosomal marker, amelogenin. This demonstrates that identification of sex using standard SNP assays can be erroneous in highly inbred individuals.