Article link: https://doi.org/10.1016/j.jclinane.2026.112324

This dataset includes aggregate summary data from 18,887 eligible surgical encounters contributed by 12,070 unique patients included in the associated retrospective cohort study of perioperative substance use-related treatment and referral. No patient-level or encounter-level records are provided.

The study included surgical encounters involving patients with at least moderate-risk unhealthy alcohol use as measured by the Alcohol Use Disorders Identification Test–Consumption (AUDIT-C) who had not received substance use-related behavioral or pharmacologic treatment in the 90 days preceding surgery.

Description of the data and file structure

Data are provided in Excel format: Microsoft Excel Worksheet (.xlsx)

The workbook Summary_Data.xlsx contains three worksheets:

Worksheet: Cohort_Summary

Description: Aggregate demographic, clinical, and surgical encounter characteristics.

Variables:

• Variable: Name of the characteristic being summarized
• Category: Category or value of the corresponding variable
• N: Number of eligible surgical encounters in the category
• Percentage: Percentage of all 18,887 eligible surgical encounters in the category

Variable (name of the characteristic being summarized): 

• Gender: Recorded gender associated with the surgical encounter (Male or Female)
• Race: Recorded race associated with the surgical encounter (Black, White, or Other)
• Encounter_Setting: Surgical encounter setting (Inpatient or Outpatient)
• Age_Group: Age at the surgical encounter, categorized as <30, 30-39, 40-49, 50-59, 60-69, 70-79, or 80+ years
• Hospital_Length_of_Stay: Hospital length of stay in days, categorized as 0, 1, 2-3, 4-7, 8-14, 15-29, or 30+ days
• ASA_Status: American Society of Anesthesiologists (ASA) Physical Status classification, a preoperative assessment of overall health status. Scores range from 1 (healthy) to 6 (declared dead). Higher scores represent poorer states of health.
  • 1, 2, 3, and 4 (unique values): ASA Physical Status categories 1 through 4
  • 5 or 6: ASA categories 5 and 6 combined
  • Missing: ASA status not available
• AUDIT-C_Score: Alcohol Use Disorders Identification Test–Consumption (AUDIT-C) score, ranging from 0 to 12, with higher scores indicating greater alcohol use risk. Only scores meeting study inclusion criteria are represented in the dataset.
• AUDIT-C_Risk_Group: Risk category derived from AUDIT-C score
  • Men: Moderate = 4-5, High = 6-7, Severe = 8-12
  • Women: Moderate = 3-5, High = 6-7, Severe = 8-12
• Anxiety_6M_Prior: Anxiety diagnosis documented in the 6 months preceding the surgical encounter (Yes/No)
• Depression_6M_Prior: Depression diagnosis documented in the 6 months preceding the surgical encounter (Yes/No)
• Substance_Use_Disorder_6M_Prior: Substance use disorder diagnosis documented in the 6 months preceding the surgical encounter (Yes/No)
• Alcohol_Use_Disorder_6M_Prior: Alcohol use disorder diagnosis documented in the 6 months preceding the surgical encounter (Yes/No)
• Procedure_Specialty: Specialty associated with the procedure (General Surgery, Interventional, Cardiothoracic Surgery, Neurosurgery, Orthopedic Surgery, Vascular Surgery, Plastic Surgery, OB/GYN, Other, and ENT, OMFS, Ophthalmology)

Worksheet: Treatment_Summary

Description: Aggregate counts and percentages of newly documented behavioral therapy, outpatient treatment/referral, and pharmacotherapy during the surgical encounter and within 90 days after discharge.

Variables:

• Period or Section: Time period or treatment represented by the row:
  • Perioperative (either period): during the surgical encounter and/or within 90 days following discharge
  • During surgical encounter: treatment documented during the surgical encounter (preceding discharge)
  • Post-discharge: treatment documented within 90 days following discharge
  • Pharmacotherapy timing: whether pharmacotherapy (naltrexone, acamprosate, and/or disulfiram) occurred during the surgical encounter, post-discharge, or during both periods
  • Pharmacotherapy regimen: medication documented
• Treatment: Type of treatment, referral, or medication
• N: Number of eligible surgical encounters meeting the treatment criteria
• Percent: Percentage of all 18,887 eligible surgical encounters meeting the treatment criteria

Time period or treatment variables:

• Any treatment or referral: One or more qualifying treatments or referrals documented
• Psychotherapy: Behavioral therapy and/or outpatient therapy or referral documented
• Behavioral therapy: Behavioral therapy documented
• Outpatient therapy/referral: Referral to and/or documentation of outpatient therapy documented
• Any pharmacotherapy: Documented receipt of or prescription of one or more of the following medications: naltrexone, disulfiram, or acamprosate
• Naltrexone: Documented receipt of or prescription of naltrexone
• Disulfiram: Documented receipt of or prescription of disulfiram
  • Exact counts fewer than 10 are reported as <10 in selected summary cells, with the corresponding percentage n/a
• Acamprosate: Documented receipt of or prescription of acamprosate
• Multiple medications: Documented receipt of or prescription of two or more of the following medications: naltrexone, disulfiram, or acamprosate

Worksheet: Treatment_by_AUDITC

Description: Aggregate treatment and referral counts and percentages stratified by AUDIT-C risk category. Percentages use the number of encounters within the relevant AUDIT-C risk category as the denominator.

Variables:

• AUDIT-C Risk Category: Moderate, High, or Severe AUDIT-C risk group
• Encounters: Number of eligible surgical encounters within the corresponding AUDIT-C risk category
• Any treatment/Referral N: Number of encounters with one or more qualifying perioperative treatment(s) or referral(s) documented
• Any Treatment/Referral %: Percentage of encounters within the risk category with one or more qualifying perioperative treatment(s) or referral(s) documented
• Psychotherapy N: Number of encounters with perioperative behavioral therapy and/or outpatient therapy or referral documented
• Psychotherapy %: Percentage of encounters within the risk category with perioperative behavioral therapy and/or outpatient therapy or referral documented
• Behavioral Therapy N: Number of encounters with perioperative behavioral therapy documented
• Behavioral Therapy %: Percentage of encounters within the risk category with documented perioperative behavioral therapy
• Outpatient Therapy/Referral N: Number of encounters with perioperative outpatient therapy or referral documented
• Outpatient Therapy/Referral %: Percentage of encounters within the risk category with documented perioperative outpatient therapy or referral
• Any pharmacotherapy N: Number of encounters with perioperative naltrexone, disulfiram, and/or acamprosate receipt or prescription documented
• Any pharmacotherapy %: Percentage of encounters within the risk category with documented receipt or prescription of perioperative naltrexone, disulfiram, and/or acamprosate
• Naltrexone N: Number of encounters with perioperative naltrexone documented
• Naltrexone %: Percentage of encounters within the risk category with documented perioperative naltrexone

AUDIT-C Risk CategoryVariables include:

• Moderate risk: AUDIT-C score of 4-5 in men and 3-5 in women
• High risk: AUDIT-C score of 6-7
• Severe risk: AUDIT-C score of 8-12

Sharing/Access information

Not applicable. These data are only shared via the Dryad platform.

Code/Software

Not applicable.

Data are provided in Microsoft Excel Worksheet (.xlsx) format.

Human subjects data

The data presented are aggregate summary data from the associated study, "Initiation of Substance Use-Related Treatments in Surgical Patients with Risky Alcohol Use." The study was reviewed by the UNMC Institutional Review Board (UNMC IRB, Protocol #0570-22-EX) and classified as exempt because it was based on a fully de-identified dataset and therefore does not constitute human subjects research from a regulatory perspective.

The underlying study data were extracted from the electronic health record and de-identified before analysis. No patient-level or encounter-level data are provided in this public dataset. Instead, only aggregate summary statistics are shared.

Human subjects data

Only summary data are provided. No individual-level data are provided.