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Data from: Geospatial mobility, non-local partners, concurrent sexual partnerships, and gender influence longitudinal STI prevalence in rural eastern Africa

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Mar 25, 2026 version files 4.39 MB

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Abstract

Mobility challenges HIV prevention efforts through associated risk behaviours and sexually transmitted infections (STIs). We characterized relationships between mobility and sexual risks on STI prevalence over time in East Africa. Geospatial mobility and sexual risk behaviours were collected in 12 communities using a sex- and HIV-stratified random sub-sample of 2,750 adults from a longitudinal cohort (2015-2019) of a HIV test-and-treat trial in Kenya and Uganda. Annual Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) testing was performed, and relationships of prevalent STIs with mobility, sexual concurrency, and higher HIV-risk sexual partners (defined as one-night stand, stranger, commercial sex worker/client, casual partner, or inherited partner/inheritor) were examined. The annual prevalence of CT or NG among 2,665 participants tested was 3.1% (95 % CI: 2.5-3.9) at baseline, 3.3% (95 % CI: 2.6-4.0) at year 1, 4.4 % (95 % CI: 3.0-5.2) at year 2, and 4.8 % (95 % CI: 4.0-5.7) at year 3. STI (CT, NG) prevalence was associated with migration in the past year, sexual partnership concurrency, being single, higher HIV-risk partners, age > 25, low household wealth, and the relationship between gender and work-related travel in past six months. The association between select STI prevalence and past six-months travel was mediated by higher HIV-risk sexual partners, partnership concurrency, out-of-town partner, and higher HIV-risk transactional sex partners. Geospatial mobility, sexual concurrency, and higher HIV-risk partnerships significantly influence longitudinal CT and/or NG prevalence in East Africa.