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Relationship between c-reactive protein-albumin ratio and prognosis in pediatric patients with severe burns

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Apr 02, 2025 version files 9.37 KB

Abstract

C-reactive protein (CRP) is a widely requested acute-phase protein. This study aimed to investigate the relationship between albumin, CRP, and CRP-albumin ratio values and hospital length of stay (LOS) in children with severe burns. A total of 150 pediatric patients who were treated in our hospital's burns clinic or burns intensive care unit due to third- and fourth-degree burns between January 2019 and September 2023 were included in the study. The mean CRP-albumin ratio was significantly lower in those hospitalized for 10 days or less than that in those hospitalized for a longer period (p<0.001). The rates of patients with high CRP-albumin ratio in those hospitalized for 21-30 days and more than 40 days were found to be significantly higher than the other groups (p<0.001). Hospital LOS was positively and significantly related to CRP-albumin ratios (p<0.001; r=0.529). In children with severe burns, low albumin levels, high CRP levels, and high CRP-albumin ratios at hospital admission may be related to clinical presentation and hospital LOS.