Skip to main content
Dryad

Data from: Amadori-glycated phosphatidylethanolamine enhances the physical stability and selective targeting ability of liposomes

Miyazawa, Taiki1; Kamiyoshihara, Reina1; Shimizu, Naoki1; Harigae, Takahiro1; Otoki, Yurika1; Ito, Junya1; Kato, Shunji2; Miyazawa, Teruo1; Nakagawa, Kiyotaka1

Published Feb 12, 2018 on Dryad. https://doi.org/10.5061/dryad.g6f6g

Data files

Feb 12, 2018 version files 17.45 KB

Click names to download individual files

Abstract

Liposomes consisting of 100% phosphatidylcholine exhibit poor membrane fusion, cellular uptake and selective targeting capacities. To overcome these limitations, we used Amadori-glycated phosphatidylethanolamine, which is universally present in animals and commonly consumed in foods. We found that liposomes containing Amadori-glycated phosphatidylethanolamine exhibited significantly reduced negative membrane potential and demonstrated high cellular uptake.