Dataset DOI: 10.5061/dryad.ncjsxkt6q

Description of the data and file structure

The serum proteomics file is in CSV format.

Column A is the protein name.

Columns B- H are percentage readings of each disease group, including healthy, stricturing CD (CDS), non-stricturing CD (CDNS), ulcerative colitis (UC), C. difficile infection (CDI), prediabetes (PD), and type 2 diabetes (T2DM).

Columns I-J are means and standard deviation of reading in columns B-H.

Columns K- P are the Z score of each disease group.

Columns Q-S are the gene names, Uniprot, and GeneIDs of each protein.

Column T is a description of each protein.

Zenodo contents

Proper citation is required if the data are generated from commercial sources. Please consult the relevant companies for guidelines.

Two Zip folders are deposited on Zenodo. Zip files are under CC-BY licenses.

Please unzip the Zip folders to retrieve additional files of RNA sequencing.

CD02, CD04, and CD05 are viewed as 10X Genomics’ SpaceRanger.

CD02, CD04, and CD05 are ileal tissue explants from stricturing CD patients.

For help, please visit https://www.10xgenomics.com/support/software/space-ranger/latest.

Please cite Space Ranger data by following the guidelines: https://www.10xgenomics.com/support/software/cell-ranger/latest/miscellaneous/cr-citations

CDHIF RNA-seq file: A = control; B=CDSE; C=CDSE+Fidaxomicin.

The folders contain heatmaps, IPA analysis, and gene lists.

Please cite Ingenuity Pathway Analysis (IPA) data by following the guidelines:

https://digitalinsights.qiagen.com/citation-guidelines/#:~:text=When%20citing%20QIAGEN%20IPA%20in,30(4):523%E2%80%9330

If you have questions, please ask Dr. Hon Wai Koon for additional information.

Human subjects data

We do not provide personally identifiable information. All samples are coded. We could not obtain explicit consent from the participants because we did not have any information about the patients.