Dataset DOI: 10.5061/dryad.pzgmsbd12

Description of the data and file structure

This dataset contains all files required to reproduce the results in the publication “Non-surgical Bioelectronic Implant for Targeted Focal Brain Stimulation.”

Files and variables

File: Data.xlsx

Description: Source data for figures in the main text, extended data, and supplementary figures

Variables

• The following sheets are present in the data.xlsx file - each named and corresponding to the source data for the figures
  • Fig. 2d-h
  • Fig. 3c, Fig. 3g-i
  • Fig. 4f-g
  • Fig. 5a-f
  • Fig. E1
  • Fig. E2
  • Fig. E3
  • Fig. E5
  • Fig. E7
  • Fig. E9
  • Fig. E10
  • Fig. S5
  • Fig. S6
  • Fig. S9
  • Fig. S11

File: Fig2b.zip

Description: Raw SEM images corresponding to the figure

File: FigE3.zip

Description: Raw SEM images corresponding to the figure

File: FigE5.zip

Description: contains raw images for Fig. E5d. Additionally, corresponding processed images can be found in the following sub-folders:

• NCB0184_22_014_crop-MaxIP_crop - processed .tiff images for Fig. E5d
• NCB0184_22_014_crop-MaxIPcrop_noDAPI - processed .tiff images for Fig. E5d

File: FigE9.zip

Description: Raw data/image as well as processed data/image to reproduce the figure 

File: FigS10.zip

Description: Raw data in text format, matlab code to analyze the data and a processed image corresponding to the figure 

File: FigS13.zip

Description: matlab code used to produce the figure and the associated processed figures generated using the code

File: FigE6.zip

Description: raw data/processed images corresponding to regression analysis (including the raw unprocessed images)

File: FigS12.zip

Description: raw data in .doric fomat (matlab code to process it is present in Fig. E8, or Fig. 4h), corresponding processed .mat files for direct usage and the plots associated with the figure

File: FigE8.zip

Description: raw data for the two control datasets in .doric fomat (and an associated matlab code to process it), corresponding processed .mat files for direct usage and the plots associated with the figure

File: Fig3.zip

Description: Contains data corresponding to sub-figure panels

• Fig. 3a - FIB/SEM raw images to reproduce the figure 
• Fig. 3b - raw and processed images to reproduce the figure 
• Fig. 3d-f - contains raw images for Fig. 3d, 3e, and 3f. Additionally, processed images can be found in the following sub-folders:
  • Fig. 3d
  • Fig. 3e
  • Fig. 3f
• Fig. 3h - processed figures panels can be found. Additionally, the data corresponding to regression analysis (including the raw unprocessed images) can be found in the following sub-folder
  • regressional_analysis
• Fig. 3i - processed figures panels can be found. Raw/unprocessed data can be found in Fig. 3h folder

File: Fig4.zip

Description: Contains data corresponding to sub-figure panels

• Fig. 4b-e - contains folders with raw/processed images for Fig. 4b, 4c, 4d, and 4e
  • Fig. 4b - raw and processed images to reproduce the figure 
  • Fig. 4c - raw and processed images to reproduce the figure 
  • Fig. 4d - raw and processed images to reproduce the figure 
  • Fig. 4e - raw and processed images to reproduce the figure 
• Fig. 4h - raw data in .doric fomat (and an associated matlab code to process it), corresponding processed .mat file and the plots associated with the figure

File: Fig5.zip

Description: Contains data corresponding to sub-figure panels

• Fig. 5a - processed figures and a sub-folder containing the raw data
  • Data - contains the video recordings, matlab scripts to process the data for the experimental and control groups (SY127-131 - 3d control, SY132-136 - 3d expt; SY117-121 - 12d control, SY122-126 - 12d expt)
• Fig. 5b - processed figures. Raw data can be found in Fig. 5a subfolder "Data"

Code/software

The analyses were performed using MATLAB 2023. All codes and functions are provided within the dataset to ensure reproducibility.