Gold nanochips with molecularly imprinted polymer coating for explosives sensing: Surface-enhanced Raman scattering approach
Data files
Sep 17, 2025 version files 531.02 KB
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Fig_4_and_6.opju
113.31 KB
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Fig_5_revision.opju
124.75 KB
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Fig_5.opju
116 KB
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Fig_7.opju
172.04 KB
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README.md
4.91 KB
Abstract
This research is aimed at developing a sensor that is both sensitive and selective for detecting explosives, and to examine its surface enhanced Raman scattering (SERS) response. Molecularly imprinted polymers (MIPs), commonly used as synthetic receptors in sensors for the selective detection of molecules without prior analytic treatments, have been combined with optical sensors. This integration, especially in combination with localized surface plasmon resonance (LSPR) technology, represents a promising strategy for identifying explosives. In this paper, a sensor based on a gold nanostructure array deposited onto a glass substrate (gold nanochip), followed by the fabrication of a MIP layer using the photochemical polymerization method with 4-nitrophenol (4-NP) as a template molecule, is considered. The selectivity of the sensor was assessed by comparing the SERS and LSPR responses against 4-NP and other chemical analogs of nitro-containing explosives. Notably, this technique not only ensures sensor selectivity, but is also capable of detecting analytes at concentrations as low as 100 μM.
Dataset DOI: https://doi.org/10.5061/dryad.qrfj6q5v7
Description of the data and file structure
We have submitted our raw data and graphs of surface enhanced Raman scattering (SERS) spectral response of gold nanostructure (AuNS) arrays with (graph Fig4 in Fig_4_and_6.opju) and without (graph Fig6 in Fig_4_and_6.opju) a molecularly imprinted polymer (MIP) to the addition of an analyte molecule 4-nitrophenol (4-NP), as well as similar SERS spectral response data of AuNS–MIP sensor to other chemical analogues of explosives (Fig_5.opju). We have also added localized surface plasmon resonance (LSPR) spectra for MIP selectivity comparison (Fig_7.opju).
All data files were created in OriginPro 2018 (b9.5.1.195). To open an .opju file, you need a version of OriginLab software (2018 or later) or the free Origin Viewer from OriginLab.
Files and variables
File: Fig_4_and_6.opju
Description:
File contains 3 tables (AuNS-MIP substrate, 4-NP on AuNS-MIP substrate, 4-NP on AuNS substrate) and 2 graphs (Fig4, Fig6).
Each of the 3 tables has 2 columns. The first column contains Raman shift values in cm-1, which correspond to a wavelength difference between the excitation wavelength and Raman scattering wavelength. The second column contains Raman scattering intensity measured in arbitrary (relative) units.
Tables:
- AuNS-MIP substrate contains SERS data for Raman scattering on a nanochip with gold nanostructures with a molecularly imprinted polymer and serves as a baseline for Fig4.
- 4-NP on AuNS-MIP substrate contains SERS data for Raman scattering on a nanochip with gold nanostructures with a molecularly imprinted polymer after addition of 4-NP, and is used in both Fig4 and Fig6 to compare the selectivity of MIP.
- 4-NP on AuNS substrate contains SERS data for Raman scattering on a nanochip with gold nanostructures without a molecularly imprinted polymer, after addition of 4-NP, and is used in Fig6.
Graphs:
- Fig4 shows SERS spectra before (black) and after the addition of 100 µM 4-NP solution (red) onto the surface of the 4-NP-imprinted AuNS-MIP plasmonic sensor.
- Fig6 shows SERS spectra of 4-NP on the surface of Au nanochip without MIP coating (black) and Au nanochip with 4-NP-imprinted MIP coating (red).
File: Fig_5.opju
Description:
File contains 4 tables (5NI, 4NT, 4NP, 1NN) and 1 graph (Fig5).
Each of 4 tables has 2 columns. The first column contains Raman shift values in cm-1, which correspond to a wavelength difference between excitation wavelength and Raman scattering wavelength. The second column contains Raman scattering intensity measured in arbitrary (relative) units.
Tables 5NI, 4NT, 4NP, 1NN contains SERS data for Raman scattering on a nanochip with gold nanostructures with a molecularly imprinted polymer for each of corresponding molecules : 5-nitroisoquinoline (5-NI), 4-nitrotoluene (4-NT), 4-nitrophenol (4-NP) and 1-nitronaphthalene (1-NN).
Graph Fig5 contains SERS spectra of the mentioned analytes on the surface of the 4-NP-imprinted AuNS-MIP plasmonic sensor.
File: Fig_5_revision.opju
Description:
File contains same tables and graph as Fig_5.opju with the exception of the 4NP table, which was incorrect in the original draft and was changed during the revision process to the correct one.
File: Fig_7.opju
Description:
File contains 4 tables (sample_1_center.absorb, sample_1_4NT.absorb, sample_1_4NP.absorb, Book1) and 1 graph (Graph1).
Tables contain raw data for LSPR absorbance of 4-NP imprinted AuNS-MIP nanochip in 3 points:
- sample_1_center.absorb - MIP without any analytes
- sample_1_4NT.absorb - MIP with a 4-NT droplet
- sample_1_4NP.absorb - MIP with a 4-NP droplet.
These tables contain 3 main columns with data. The first column contains the spectrometer pixel index (starting from 0, with an increase step of 1). The second column contains the light wavelength in nanometers (nm). Third column contains absorbance intensity in optical density units.
Table Book1 contains summarized data from tables sample_1_center.absorb, sample_1_4NT.absorb, and sample_1_4NP.absorb. The first column contains light wavelength in nanometers (nm), columns 2-4 contain absorbance intensity in optical density units for MIP, MIP+4NT, and MIP+4NP, respectively.
Graph Graph1 shows light extinction spectra of AuNS-MIP plasmonic sensor for free 4-NP-imprinted MIP (black) and MIP with deposited 4-NP (blue) and 4-NT (red). Arrows indicate the LSPR peak positions.