Caddell, Taylor 1 ; Mulloy, Rory2; Corcoran, Jennifer2; McCormick, Craig1 ; Pringle, Eric1

Published Apr 27, 2026 on Dryad. https://doi.org/10.5061/dryad.rjdfn2zs6

This dataset contains all biological replicates for immunoblots and immunofluorescence microscopy images associated with the manuscript "Coronavirus M protein disperses the trans-Golgi network and inhibits anterograde protein trafficking in the secretory pathway". These figures demonstrate that the SARS-CoV-2 M protein inhibits the ATF6 branch of the unfolded protein response but not the PERK or IRE1 branches. Additionally, the SARS-CoV-2 M protein localizes to the cis-Golgi while leading to dispersal of the trans-Golgi network and preventing anterograde trafficking of host proteins beyond the cis-Golgi. Furthermore, SARS-CoV-2 M recruits cholesterol to this site. This data provides a greater understanding of how SARS-CoV-2 M restructures the host secretory pathway which consequentially inhibits host protein trafficking and secretion, outlining a novel role for coronavirus M proteins beyond assembly and structure.

Dataset DOI: 10.5061/dryad.rjdfn2zs6

Description of the data and file structure

This dataset was collected in conjunction with data outlined in the associated manuscript to demonstrate the novel role of coronavirus Membrane (M) proteins. This dataset demonstrate that M proteins localize to the cis-Golgi and alter host protein trafficking and secretion through the secretory pathway within the cell.

Files and variables

File: Figure_2B_Actin_Blot_Bio_Rep_1.tif

Description: Raw immunoblot image of beta-actin for biological replicate 1 of Figure 2B within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2B in with manuscript.

File: Figure_2B_Actin_Blot_Bio_Reps_2___3.jpg

Description: Raw immunoblot image of beta-actin for biological replicates 2 and 3 of Figure 2B within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2B in with manuscript.

File: Figure_2B_BiP_Blot_Bio_Rep_1.tif

Description: Raw immunoblot image of BiP for biological replicate 1 of Figure 2B within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2B in with manuscript.

File: Figure_2B_BiP_Blot_Bio_Reps_2___3.jpg

Description: Raw immunoblot image of BiP for biological replicates 2 and 3 of Figure 2B within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2B in with manuscript.

File: Figure_2B_CHOP_Bio_Rep_2.tif

Description: Raw immunoblot image of CHOP for biological replicate 2 of Figure 2B within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2B in with manuscript.

File: Figure_2B_CHOP_Blot_Bio_Rep_1.jpg

Description: Raw immunoblot image of CHOP for biological replicate 1 of Figure 2B within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2B in with manuscript.

File: Figure_2B_E_Blot_Bio_Reps_2___3.jpg

Description: Raw immunoblot image of E for biological replicates 2 and 3 of Figure 2B within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2B in with manuscript.

File: Figure_2B_E_Blot_Bio_Rep_1.tif

Description: Raw immunoblot image of E for biological replicate 1 of Figure 2B within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2B in with manuscript.

File: Figure_2B_M_Blot_Bio_Reps_2___3.jpg

Description: Raw immunoblot image of M for biological replicates 2 and 3 of Figure 2B within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2B in with manuscript.

File: Figure_2B_PERK_Blot_Bio_Rep_1.tif

Description: Raw immunoblot image of PERK for biological replicate 1 of Figure 2B within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2B in with manuscript.

File: Figure_2B_M_Blot_Bio_Rep_1.tif

Description: Raw immunoblot image of M for biological replicate 1 of Figure 2B within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2B in with manuscript.

File: Figure_2B_PERK_Blot_Bio_Reps_2___3.jpg

Description: Raw immunoblot image of PERK for biological replicates 2 and 3 of Figure 2B within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2B in with manuscript.

File: Figure_2B_Spike_Blot_Bio_Reps_2___3.jpg

Description: Raw immunoblot image of Spike for biological replicates 2 and 3 of Figure 2B within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2B in with manuscript.

File: Figure_2B_Spike_Blot_Bio_Rep_1.tif

Description: Raw immunoblot image of Spike for biological replicate 1 of Figure 2B within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2B in with manuscript.

File: Figure_2B_XBP1s_Blot_Bio_Rep_1.tif

Description: Raw immunoblot image of XBP1s for biological replicate 1 of Figure 2B within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2B in with manuscript.

File: Figure_2B_XBP1s_Blot_Bio_Reps_2___3.jpg

Description: Raw immunoblot image of XBP1s for biological replicates 2 and 3 of Figure 2B within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2B in with manuscript.

File: Figure_2C_Actin_Blot_Bio_Rep_1.tif

Description: Raw immunoblot image of beta-actin for biological replicate 1 of Figure 2C within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2C in with manuscript.

File: Figure_2C_Actin_Blot_Bio_Reps_2___3.jpg

Description: Raw immunoblot image of beta-actin for biological replicates 2 and 3 of Figure 2C within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2C in with manuscript.

File: Figure_2C_BiP_Blot_Bio_Rep_1.tif

Description: Raw immunoblot image of BiP for biological replicate 1 of Figure 2C within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2C in with manuscript.

File: Figure_2C_BiP_Blot_Bio_Reps_2___3.jpg

Description: Raw immunoblot image of BiP for biological replicates 2 and 3 of Figure 2C within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2C in with manuscript.

File: Figure_2C_CHOP_Blot_Bio_Rep_1.tif

Description: Raw immunoblot image of CHOP for biological replicate 1 of Figure 2C within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2C in with manuscript.

File: Figure_2C_CHOP_Blot_Bio_Rep_2.tif

Description: Raw immunoblot image of CHOP for biological replicate 2 of Figure 2C within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2C in with manuscript.

File: Figure_2C_M_Blot_Bio_Rep_1.tif

Description: Raw immunoblot image of M for biological replicate 1 of Figure 2C within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2C in with manuscript.

File: Figure_2C_M_Blot_Bio_Reps_2___3.jpg

Description: Raw immunoblot image of M for biological replicates 2 and 3 of Figure 2C within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2C in with manuscript.

File: Figure_2C_PERK_Blot_Bio_Rep_1.tif

Description: Raw immunoblot image of PERK for biological replicate 1 of Figure 2C within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2C in with manuscript.

File: Figure_2C_PERK_Blot_Bio_Reps_2___3.jpg

Description: Raw immunoblot image of PERK for biological replicates 2 and 3 of Figure 2C within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2C in with manuscript.

File: Figure_2C_Spike_Blot_Bio_Reps_2___3.jpg

Description: Raw immunoblot image of Spike for biological replicates 2 and 3 of Figure 2C within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2C in with manuscript.

File: Figure_2C_Spike_Blot_Bio_Rep_1.tif

File: Figure_2C_XBP1s_Blot_Bio_Reps_2___3.jpg

Description: Raw agarose image of XBP1s for biological replicates 2 and 3 of Figure 2C within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2C in with manuscript.

File: Figure_2C_XBP1s_Blot_Bio_Rep_1.tif

File: Figure_2D_Gel_Bio_Rep_1.tif

Description: Raw image of agarose gel displaying results from biological replicate 1 of the XBP1s splicing assay. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2D in with manuscript.

File: Figure_2D_Gel_Bio_Reps_2___3.jpg

Description: Raw image of agarose gel displaying results from biological replicates 2 and 3 of the XBP1s splicing assay. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 2D in with manuscript.

File: Figure_4A_EV_Image_Bio_Rep_2.tif

Description: Composite max intensity projection of empty vector condition for Figure 4A biological replicate 2. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 4A in with manuscript.

File: Figure_4A_M_Image_Bio_Rep_1.png

Description: Composite max intensity projection of M condition for Figure 4A biological replicate 1. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 4A in with manuscript.

File: Figure_4A_M_Image_Bio_Rep_2.tif

Description: Composite max intensity projection of M condition for Figure 4A biological replicate 2. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 4A in with manuscript.

File: Figure_4A_EV_Image_Bio_Rep_1.png

Description: Composite max intensity projection of empty vector condition for Figure 4A biological replicate 1. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 4A in with manuscript.

File: Figure_4B_EV_Image_Bio_Rep_1.png

Description: Composite max intensity projection of empty vector condition for Figure 4B biological replicate 1. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 4B in with manuscript.

File: Figure_4B_EV_Image_Bio_Rep_2.tif

Description: Composite max intensity projection of empty vector condition for Figure 4B biological replicate 2. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 4B in with manuscript.

File: Figure_4B_M_Image_Bio_Rep_2.tif

Description: Composite max intensity projection of M condition for Figure 4B biological replicate 2. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 4B in with manuscript.

File: Figure_4B_M_Image_Bio_Rep_Rep_1.png

Description: Composite max intensity projection of M condition for Figure 4B biological replicate 1. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 4B in with manuscript.

File: Figure_4C_Mock___GM130_Image_Bio_Rep_1.png

Description: Composite max intensity projection of mock infected GM130 stained condition for Figure 4C biological replicate 1. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 4C in with manuscript.

File: Figure_4C_Mock___GM130_Image_Bio_Rep_3.tif

Description: Composite max intensity projection of mock infected GM130 stained condition for Figure 4C biological replicate 3. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 4C in with manuscript.

File: Figure_4C_Mock___GM130_Image_Bio_Rep_2.tif

Description: Composite max intensity projection of mock infected GM130 stained condition for Figure 4C biological replicate 2. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 4C in with manuscript.

File: Figure_4C_Mock___TGOLN2_Image_Bio_Rep_2.tif

Description: Composite max intensity projection of mock infected TGOLN2 stained condition for Figure 4C biological replicate 2. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 4C in with manuscript.

File: Figure_4C_Mock___TGOLN2_Image_Bio_Rep_1.png

Description: Composite max intensity projection of mock infected TGOLN2 stained condition for Figure 4C biological replicate 1. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 4C in with manuscript.

File: Figure_4C_SARS2___GM130_Image_Bio_Rep_1.png

Description: Composite max intensity projection of SARS2 infected GM130 stained condition for Figure 4C biological replicate 1. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 4C in with manuscript.

File: Figure_4C_Mock___TGOLN2_Image_Bio_Rep_3.tif

Description: Composite max intensity projection of mock infected TGOLN2 stained condition for Figure 4C biological replicate 3. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 4C in with manuscript.

File: Figure_4C_SARS2___GM130_Image_Bio_Rep_2.tif

Description: Composite max intensity projection of SARS2 infected GM130 stained condition for Figure 4C biological replicate 2. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 4C in with manuscript.

File: Figure_4C_SARS2___TGOLN2_Image_Bio_Rep_1.png

Description: Composite max intensity projection of SARS2 infected TGOLN2 stained condition for Figure 4C biological replicate 1. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 4C in with manuscript.

File: Figure_4C_SARS2___GM130_Image_Bio_Rep_3.tif

Description: Composite max intensity projection of SARS2 infected GM130 stained condition for Figure 4C biological replicate 3. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 4C in with manuscript.

File: Figure_4C_SARS2___TGOLN2_Image_Bio_Rep_2.tif

Description: Composite max intensity projection of SARS2 infected TGOLN2 stained condition for Figure 4C biological replicate 2. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 4C in with manuscript.

File: Figure_4C_SARS2___TGOLN2_Image_Bio_Rep_3.tif

Description: Composite max intensity projection of SARS2 infected TGOLN2 stained condition for Figure 4C biological replicate 3. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 4C in with manuscript.

File: Figure_5B_24_hr_Biotin_EV_Image_Bio_Rep_1.png

Description: Composite max intensity projection of empty vector 24 hour biotin treated condition for Figure 5B biological replicate 1. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 5B in with manuscript.

File: Figure_5B_24_hr_Biotin_EV_Image_Bio_Rep_2.tif

Description: Composite max intensity projection of empty vector 24 hour biotin treated condition for Figure 5B biological replicate 2. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 5B in with manuscript.

File: Figure_5B_24_hr_Biotin_EV_Image_Bio_Rep_3.tif

Description: Composite max intensity projection of empty vector 24 hour biotin treated condition for Figure 5B biological replicate 3. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 5B in with manuscript.

File: Figure_5B_24_hr_Biotin_M_Image_Bio_Rep_2.tif

Description: Composite max intensity projection of M 24 hour biotin treated condition for Figure 5B biological replicate 2. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 5B in with manuscript.

File: Figure_5B_24_hr_Biotin_M_Image_Bio_Rep_1.png

Description: Composite max intensity projection of M 24 hour biotin treated condition for Figure 5B biological replicate 1. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 5B in with manuscript.

File: Figure_5B_No_Biotin_EV_Image_Bio_Rep_1.png

Description: Composite max intensity projection of empty vector no biotin treated condition for Figure 5B biological replicate 1. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 5B in with manuscript.

File: Figure_5B_24_hr_Biotin_M_Image_Bio_Rep_3.tif

Description: Composite max intensity projection of M 24 hour biotin treated condition for Figure 5B biological replicate 3. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 5B in with manuscript.

File: Figure_5B_No_Biotin_EV_Image_Bio_Rep_2.tif

Description: Composite max intensity projection of empty vector no biotin treated condition for Figure 5B biological replicate 2. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 5B in with manuscript.

File: Figure_5B_No_Biotin_M_Image_Bio_Rep_1.png

Description: Composite max intensity projection of M no biotin treated condition for Figure 5B biological replicate 1. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 5B in with manuscript.

File: Figure_5B_No_Biotin_EV_Image_Bio_Rep_3.tif

Description: Composite max intensity projection of empty vector no biotin treated condition for Figure 5B biological replicate 3. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 5B in with manuscript.

File: Figure_5B_No_Biotin_M_Image_Bio_Rep_2.tif

Description: Composite max intensity projection of M no biotin treated condition for Figure 5B biological replicate 2. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 5B in with manuscript.

File: Figure_5B_No_Biotin_M_Image_Bio_Rep_3.tif

Description: Composite max intensity projection of M no biotin treated condition for Figure 5B biological replicate 3. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 5B in with manuscript.

File: Figure_6A_Calnexin_Blot_Bio_Reps_1___2.jpg

Description: Raw immunoblot image of Calnexin for biological replicates 1 and 2 of Figure 6A within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 6A in with manuscript.

File: Figure_6A_Calnexin_Blot_Bio_Reps_3___4.jpg

Description: Raw immunoblot image of Calnexin for biological replicates 3 and 4 of Figure 6A within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 6A in with manuscript.

File: Figure_6A_Caveolin_Blot_Bio_Reps_1___2.jpg

Description: Raw immunoblot image of Caveolin for biological replicates 1 and 2 of Figure 6A within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 6A in with manuscript.

File: Figure_6A_Caveolin_Blot_Bio_Reps_3__4.jpg

Description: Raw immunoblot image of Caveolin for biological replicates 3 and 4 of Figure 6A within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 6A in with manuscript.

File: Figure_6A_ERGIC53_Blot_Bio_Reps_1___2.jpg

Description: Raw immunoblot image of ERGIC53 for biological replicates 1 and 2 of Figure 6A within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 6A in with manuscript.

File: Figure_6A_ERGIC53_Blot_Bio_Reps_3___4.jpg

Description: Raw immunoblot image of ERGIC53 for biological replicates 3 and 4 of Figure 6A within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 6A in with manuscript.

File: Figure_6A_M_Blot_Bio_Reps_1___2.tif

Description: Raw immunoblot image of M for biological replicates 1 and 2 of Figure 6A within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 6A in with manuscript.

File: Figure_6A_M_Blot_Bio_Reps_3___4.jpg

Description: Raw immunoblot image of M for biological replicates 3 and 4 of Figure 6A within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 6A in with manuscript.

File: Figure_6B_EGFP___D4H_Image_Bio_Rep_1.png

Description: Composite max intensity projection of EGFP with D4H for biological replicate 1 of Figure 6B within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 6B in with manuscript.

File: Figure_6B_EGFP___D4H_Image_Bio_Rep_2.tif

Description: Composite max intensity projection of EGFP with D4H for biological replicate 2 of Figure 6B within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 6B in with manuscript.

File: Figure_6B_MEGFP___D4H_Image_Bio_Rep_1.png

Description: Composite max intensity projection of MEGFP with D4H for biological replicate 1 of Figure 6B within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 6B in with manuscript.

File: Figure_6B_EGFP___D4H_Image_Bio_Rep_3.tif

Description: Composite max intensity projection of EGFP with D4H for biological replicate 3 of Figure 6B within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 6B in with manuscript.

File: Figure_6B_MEGFP___D4H_Image_Bio_Rep_2.tif

Description: Composite max intensity projection of MEGFP with D4H for biological replicate 2 of Figure 6B within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 6B in with manuscript.

File: Figure_6B_MEGFP___D4H_Image_Bio_Rep_3.tif

Description: Composite max intensity projection of MEGFP with D4H for biological replicate 3 of Figure 6B within the manuscript. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 6B in with manuscript.

File: Figure_6D_M-mCardinal___BODIPY_Image_Bio_Rep_2.tif

Description: Composite max intensity projection of M-mCardinal with BODIPY-cholesterol for biological replicate 2 of Figure 6D. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 6D in with manuscript.

File: Figure_6D_M-mCardinal___BODIPY_Image_Bio_Rep_1.png

Description: Composite max intensity projection of M-mCardinal with BODIPY-cholesterol for biological replicate 1 of Figure 6D. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 6D in with manuscript.

File: Figure_6D_M-mCardinal___BODIPY_Image_Bio_Rep_3.tif

Description: Composite max intensity projection of M-mCardinal with BODIPY-cholesterol for biological replicate 3 of Figure 6D. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 6D in with manuscript.

File: Figure_6D_mCardinal___BODIPY_Image_Bio_Rep_1.png

Description: Composite max intensity projection of mCardinal with BODIPY-cholesterol for biological replicate 1 of Figure 6D. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 6D in with manuscript.

File: Figure_6D_mCardinal___BODIPY_Image_Bio_Rep_2.tif

Description: Composite max intensity projection of mCardinal with BODIPY-cholesterol for biological replicate 2 of Figure 6D. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 6D in with manuscript.

File: Figure_6D_mCardinal___BODIPY_Image_Bio_Rep_3.tif

Description: Composite max intensity projection of mCardinal with BODIPY-cholesterol for biological replicate 3 of Figure 6D. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Figure 6D in with manuscript.

File: Sup._Figure_2A_Mock___GM130_Image_Bio_Rep_3.tif

Description: Composite max intensity projection of mock infection and GM130 staining for biological replicate 3 of Supplementary Figure 2A. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Supplementary Figure 2A in with manuscript.

File: Sup._Figure_2A_Mock___GM130_Image_Bio_Rep_2.png

Description: Composite max intensity projection of mock infection and GM130 staining for biological replicate 2 of Supplementary Figure 2A. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Supplementary Figure 2A in with manuscript.

File: Sup._Figure_2A_Mock___GM130_Image_Bio_Rep_1.tif

Description: Composite max intensity projection of mock infection and GM130 staining for biological replicate 1 of Supplementary Figure 2A. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Supplementary Figure 2A in with manuscript.

File: Sup._Figure_2A_Mock___TGOLN2_Image_Bio_Rep_2.png

Description: Composite max intensity projection of mock infection and TGOLN2 staining for biological replicate 2 of Supplementary Figure 2A. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Supplementary Figure 2A in with manuscript.

File: Sup._Figure_2A_Mock___TGOLN2_Image_Bio_Rep_1.tif

Description: Composite max intensity projection of mock infection and TGOLN2 staining for biological replicate 1 of Supplementary Figure 2A. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Supplementary Figure 2A in with manuscript.

File: Sup._Figure_2A_Mock___TGOLN2_Image_Bio_Rep_3.tif

Description: Composite max intensity projection of mock infection and TGOLN2 staining for biological replicate 3 of Supplementary Figure 2A. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Supplementary Figure 2A in with manuscript.

File: Sup._Figure_2A_OC43___GM130_Image_Bio_Rep_1.tif

Description: Composite max intensity projection of OC43 infection and GM130 staining for biological replicate 1 of Supplementary Figure 2A. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Supplementary Figure 2A in with manuscript.

File: Sup._Figure_2A_OC43___GM130_Image_Bio_Rep_2.png

Description: Composite max intensity projection of OC43 infection and GM130 staining for biological replicate 2 of Supplementary Figure 2A. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Supplementary Figure 2A in with manuscript.

File: Sup._Figure_2A_OC43___GM130_Image_Bio_Rep_3.tif

Description: Composite max intensity projection of OC43 infection and GM130 staining for biological replicate 3 of Supplementary Figure 2A. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Supplementary Figure 2A in with manuscript.

File: Sup._Figure_2A_OC43___TGOLN2_Image_Bio_Rep_3.tif

Description: Composite max intensity projection of OC43 infection and TGOLN2 staining for biological replicate 3 of Supplementary Figure 2A. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Supplementary Figure 2A in with manuscript.

File: Sup._Figure_2A_OC43___TGOLN2_Image_Bio_Rep_1.tif

Description: Composite max intensity projection of OC43 infection and TGOLN2 staining for biological replicate 1 of Supplementary Figure 2A. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Supplementary Figure 2A in with manuscript.

File: Sup._Figure_2A_OC43___TGOLN2_Image_Bio_Rep_2.png

Description: Composite max intensity projection of OC43 infection and TGOLN2 staining for biological replicate 2 of Supplementary Figure 2A. Samples were subjected to conditions and collections parameters as outlined in the figure legend of Supplementary Figure 2A in with manuscript.

Data from: Coronavirus M protein disperses the trans-Golgi network and inhibits anterograde protein trafficking in the secretory pathway

Data files

Abstract

README: Data from: Coronavirus M protein disperses the trans-Golgi network and inhibits anterograde protein trafficking in the secretory pathway