This dataset supports the effect of mating on the lifespan of adults (males and females) of Ae. albopictus as well as the effect of blood meal frequency (none, one, and two meals) on the biodemographic characteristics: ( lifespan, egg production, number of pupae, pupation percentage, number of male offsprings, number of female offsprings, ratio of male/female offsprings). The population was collected in the vicinity of Volos and Larissa, Thessaly, Greece, and the experiments were conducted under controlled laboratory conditions. Descriptive and inferential statistics were performed. The effect of mating, sex, and their interaction on adult lifespan was explored with the Cox proportional hazards model. The comparison of virgin and mated males and females in terms of their lifespan was conducted with the Log-rank (Mantel-Cox) test. The number of mosquitoes tested for each sex and each mating treatment (virgin, mated) was equal to 50. The effect of blood meals (none, one, and two) on the lifespan of mated female adults was explored using the Cox proportional hazards model. Pairwise comparison was performed with the Log-rank (Mantel-Cox) test and the number of mosquitoes tested was 50, 42, and 47, respectively. Generalized Linear Models (GLMs) were used to test the effect of blood meals (one and two blood meals) on egg production, number of pupae, pupation percentage, number of adult offsprings, number of males offsprings, number of female offsprings, and ratio of male/female offsprings. The number of female mosquitoes tested was 42 and 47 respectively. The paired t - test was used to reveal differences in biodemographic parameters after one and two blood meals. The number of female mosquitoes tested was 47. The significance level was set at α = 0.05. Data analysis and graph was performed with the statistical package IBM SPSS 25 (SPSS Inc., Chicago, IL, USA). For each experiment, a mosquito population originating from the same generation was used. Therefore, the population did not have sufficient time period to become acclimated to the laboratory conditions and any fitness cost induced was minimal enough to be regarded as negligible.