Difluoroacetic acid (DFA): Daphnia acute toxicity, algal toxicity, and physical and chemical properties
Data files
Nov 09, 2026 version files 45.05 MB
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31996258_DFA_Mutagenic_Ames_Final_Report.pdf
2.36 MB
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31996259_DFA_Acute_Daphnia_Ecotoxicology_Final_Report_502395.pdf
2.34 MB
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31996260_DFA_Acute_Algae_Ecotoxicology_Final_Report_502395.pdf
4.57 MB
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31996261_DFA_ready_biodeg.PDF
3.20 MB
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31996264_DFA_Physical_Chemistry_Water_Solubility_Final_Report.pdf
2.56 MB
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31996266_DFA_Physical_Chemistry_IR_Final_Report.pdf
2.56 MB
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31996267_DFA_Physical_Chemistry_UV_VIS_Final_Report.pdf
2.59 MB
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31996269_DFA_Physical_Chemistry_MP_BP_Final_Report.pdf
2.52 MB
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31996270_DFA_Physical_Chemistry_Density_Final_Report.pdf
2.50 MB
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31996271_DFA_Physical_Chemistry_Vapor_Pressure_Final_Report.pdf
2.45 MB
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31996272_DFA_Physical_Chemistry_Surface_Tension_Final_Report.pdf
2.48 MB
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31996273_DFA_Physical_Chemistry_Flash_Point_Final_Report.pdf
2.45 MB
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31996274_DFA_Physical_Chemistry_Flammability_Final_Report.pdf
2.46 MB
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31996275_DFA_Physical_Chemistry_Pyrophoric_Properties_Final_Report.pdf
2.45 MB
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31996276_DFA_Physical_Chemistry_Explosive_Properties_Final_Report.pdf
2.45 MB
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31996277_DFA_Physical_Chemistry_Auto_Ignition_Final_Report.pdf
2.49 MB
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31996278_DFA_oxidizing_properties.PDF
2.17 MB
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31996279_DFA_Physical_Chemistry_HNMR_Final_Report.pdf
421.51 KB
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README.md
3.54 KB
Abstract
Aquatic toxicity data for per- and polyfluoroalkyl substances (PFAS) are generally limited; consequently, few water quality standards protective of aquatic life for individual PFAS have been developed by regulatory agencies. In response to regulatory needs, a manufacturer conducted experimental studies to measure physicochemical properties and aquatic toxicity of short-chain per- and polyfluoroalkyl carboxylic acids (PFCAs) including difluoroacetic acid (DFA; CASRN 381-73-7). Aquatic toxicity was investigated using acute guideline toxicity tests in algae (Raphidocelis subcapitata) and invertebrates (Daphnia magna). Physical and chemical properties including melting point, boiling point, density, vapor pressure, surface tension, water solubility, flammability in contact with water, UV-Vis absorption spectra, infrared absorption spectrum, pyrophoric properties, explosiveness, oxidizing properties, auto ignition, and flash point were also measured for DFA (acid form) in accordance with standard test guidelines. Details regarding the specific methodology and results for each aquatic toxicity study and physical or chemical property are provided in the dataset herein.
Dataset DOI: 10.5061/dryad.w0vt4b97j
Description of the data and file structure
NOTE ON REDACTIONS: These files may contain redacted information. The information that was redacted is a copyright notice and the names of key study personal to protect their privacy.
This dataset contains individual PDF files detailing the specific test methodology and results for each aquatic toxicity study and physical or chemical property measured for the short-chain per- and polyfluoroalkyl carboxylic acid (PFCA), difluoroacetic acid (DFA; CASRN 381-73-7). Several physicochemical properties including melting point, boiling point, density, vapor pressure, surface tension, water solubility, flammability in contact with water, UV-Vis absorption spectra, infrared absorption spectrum, pyrophoric properties, explosiveness, oxidizing properties, auto ignition, and flash point were experimentally measured for DFA following standard European, Organisation for Economic Co-operation and Development (OECD) and United States Environmental Protection Agency (EPA) test guidelines. In addition, the acute aquatic toxicity of DFA in the invertebrate, Daphnia magna, and algal species, Raphidocelis subcapitata, was evaluated in accordance with OECD test guidelines 202 (Daphnia magna acute immobilization test) and 201 (freshwater algal growth inhibition test), respectively.
Files and variables
File: 31996258_DFA_Mutagenic_Ames_Final_Report.pdf
Description: DFA bacterial mutagenicity (Ames)
File: 31996259_DFA_Acute_Daphnia_Ecotoxicology_Final_Report_502395.pdf
Description: DFA acute daphnia
File: 31996266_DFA_Physical_Chemistry_IR_Final_Report.pdf
Description: DFA IR spectrum
File: 31996267_DFA_Physical_Chemistry_UV_VIS_Final_Report.pdf
Description: DFA UV_Vis spectrum
File: 31996270_DFA_Physical_Chemistry_Density_Final_Report.pdf
Description: DFA density
File: 31996269_DFA_Physical_Chemistry_MP_BP_Final_Report.pdf
Description: DFA melting point and boiling point
File: 31996271_DFA_Physical_Chemistry_Vapor_Pressure_Final_Report.pdf
Description: DFA vapor pressure
File: 31996272_DFA_Physical_Chemistry_Surface_Tension_Final_Report.pdf
Description: DFA surface tension
File: 31996274_DFA_Physical_Chemistry_Flammability_Final_Report.pdf
Description: DFA flammability
File: 31996260_DFA_Acute_Algae_Ecotoxicology_Final_Report_502395.pdf
Description: DFA acute algae toxicity
File: 31996275_DFA_Physical_Chemistry_Pyrophoric_Properties_Final_Report.pdf
Description: DFA pyrophoric properties
File: 31996273_DFA_Physical_Chemistry_Flash_Point_Final_Report.pdf
Description: DFA flash point
File: 31996279_DFA_Physical_Chemistry_HNMR_Final_Report.pdf
Description: DFA proton NMR spectrum
File: 31996276_DFA_Physical_Chemistry_Explosive_Properties_Final_Report.pdf
Description: DFA explosive properties
File: 31996264_DFA_Physical_Chemistry_Water_Solubility_Final_Report.pdf
Description: DFA water solubility
File: 31996277_DFA_Physical_Chemistry_Auto_Ignition_Final_Report.pdf
Description: DFA auto ignition
File: 31996278_DFA_oxidizing_properties.PDF
Description: DFA oxidizing properties
File: 31996261_DFA_ready_biodeg.PDF
Description: DFA ready biodegredation