Data and code from: Error signals in the parvocellular division of the red nucleus, not the magnocellular division, drive adaptation in reaching
Data files
Apr 15, 2026 version files 113.03 KB
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calc_info.m
2.38 KB
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OR016_AE_spike.txt
35.42 KB
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OR016_ME_spike.txt
35.31 KB
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OR016_Target_spike.txt
35.41 KB
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plot_info.m
2.58 KB
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README.md
1.94 KB
Abstract
We examined the distinctive roles of the parvocellular (RNp) and magnocellular (RNm) divisions of the red nucleus in motor control and learning. RNp and RNm neurons encoded information on motor error (ME) during the ongoing movement and/or visually apparent error (AE) after the movement ended. Microstimulation of RNp, but not of RNm, induced a gradual increase in error in the direction opposite to the preferred direction of AE and ME. Interestingly, RNm neurons, in particular, encoded information on AE from the preceding reaching movement before the next movement took place. These results indicate that the RNp provides visual and ME signals that drive trial-by-trial adaptation through modifications of the cerebellum via the inferior olivary nucleus. Meanwhile, the RNm may participate in online motor corrections based on ME signals or in pre-movement adjustments based on the previous AE, processes that are distinct from those of RNp.
Dataset DOI: 10.5061/dryad.x95x69pwb
Description of the data and file structure
Spikes were recorded from individual neurons in the red nucleus of the monkey while they performed reaching toward a target in front.
calc_info.m calculates information on apparent error (AE), motor error (ME), and Target position (Target) encoded by a single neuron. Typical data from an RNp neuron (OR016) are provided as three txt files (OR016_AE_spike.txt, OR016_ME_spike.txt, OR016_Target_spike.txt). Code for calculating mutual information encoded by neural activity is provided with a typical data set presented in Figure 4 of the manuscript.
These text files are formatted as follows:
Each row represents data for each trial, and each column represents a parameter.
- 1st and 2nd columns: the horizontal and vertical error positions, respectively (pixel, 1pixel = 0.264mm).
- 3rd and 4th columns: the horizontal and vertical touch positions, respectively (pixel, 1pixel = 0.264mm, center = (512,332)).
- 5th column: the trial number.
- 6th column: task status (correct trial = 0).
- 7th column: the time of finger in the slot (ms).
- 8th column: the time of target onset (ms)
- 9th column: the time of release (ms).
- 10th column: the time of touch (ms).
- 11th column: reward onset (ms).
- 12th column: the duration of the reward delivery (ms).
- 13th and 14th columns: the horizontal and vertical prism displacement (mm).
- 15th column: the number of spikes of the trial.
- 16th- column: the time each spike occurred (ms).
Results of the calculation will be saved as mat files. plot_info.m plots three information curves with p-values representing the False Discovery Rate. Resulting plots reproduce Figs. 4b and 4c in the manuscript.