Data from: Polycyclic aromatic hydrocarbons can trigger hepatocyte release of extracellular vesicles by various mechanisms of action depending on their affinity for the aryl hydrocarbon receptor.

van Meteren N, Lagadic-Gossmann D, Chevanne M, Gallais I, Gobart D, Burel A, Chevance S, Gauffre F, Le Ferrec E, Sergent O

Date Published: July 11, 2019

DOI: https://doi.org/10.5061/dryad.3n39r6k

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Title Figure S1
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Description Figure S1: Dose and time response exposure in terms of cell death and proliferation in WIF-B9 cells upon PAH exposure in terms of cell death and proliferation.
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Title Figure S2
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Description Figure S2. Original pictures of western-blots from which some results are extracted for a presentation in figure 2C.
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Title Figure S3
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Description Figure S3 : PAHs do not affect the size of EVs released by WIF-B9 cells.
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Title Figure S4
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Description Figure S4 : PAHs do not affect the size of EVs released by primary rat hepatocytes.
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Title Figure S5
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Description Figure S5 : mRNA expression of CYP1A1, CYP1A2, CYP1B1 and CYP2C6 in WIF-B9 cells and primary rat hepatocytes.
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Title Figure S6
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Description Figure S6 : CYP1 activity in WIF-B9 and primary rat hepatocytes.
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Title Figure S7
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Description Figure S7 : Cell death and EV release of WIF-B9 cells and primary rat hepatocytes exposed to AhR agonist TCDD.
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Title Figure S8
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Description Figure S8 : Effects of pravastatin on cholesterol content of hepatocytes (A,B) and EVs (E) and also on bulk membrane fluidity (C,D).
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Title Supplementary Table S1
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Description Table S1: Selected PAH properties.
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Title Supplementary Table S2
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Description Table S2: Concentration of PAHs in human serum and daily intake of PAHs.
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Title Supplementary Table S3
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Description Table S3: Pre-treatment of WIF-B9 and primary rat hepatocytes.
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Title Supplementary Table S4
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Description Table S4 : Culture medium volume needed for EV isolation.
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Title Supplementary Table S5
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Description Table S5 : List of primers used for RT-qPCR experiments.
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When using this data, please cite the original publication:

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Additionally, please cite the Dryad data package:

van Meteren N, Lagadic-Gossmann D, Chevanne M, Gallais I, Gobart D, Burel A, Chevance S, Gauffre F, Le Ferrec E, Sergent O (2019) Data from: Polycyclic aromatic hydrocarbons can trigger hepatocyte release of extracellular vesicles by various mechanisms of action depending on their affinity for the aryl hydrocarbon receptor. Dryad Digital Repository. https://doi.org/10.5061/dryad.3n39r6k
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