GENERAL INFORMATION

1. Title of Dataset: Dose-Response Relationship Between Intra-peritoneal Phloretin Therapy and Water and Glucose Transport during Peritoneal Dialysis in Sprague-Dawley rats
2. Author Information
   A. Principal Investigator Contact Information
   Name: Carl Öberg
   Institution: Lund University, Medical Faculty
   Address: Box 117, SE-221 00
   Email: carl.oberg@med.lu.se
3. Date of data collection June 2022 to September 2023
4. Geographic location of data collection: Lund, Sweden
5. Information about funding sources that supported the collection of the data: Funding by the Crafoord Foundation, Lund University Medical Faculty Foundation grant YF 2020-YF0056, and The Inga-Britt and Arne Lundberg’s Research Foundation (all to C.M. Öberg).

SHARING/ACCESS INFORMATION

1. Licenses/restrictions placed on the data: -
2. Links to publications that cite or use the data: -
3. Links to other publicly accessible locations of the data: -
4. Links/relationships to ancillary data sets: -
5. Was data derived from another source? No
6. Recommended citation for this dataset: -

DATA & FILE OVERVIEW

1. File List: phloretindose.xls
2. Relationship between files, if important: -
3. Additional related data collected that was not included in the current data package: -
4. Are there multiple versions of the dataset? NO

METHODOLOGICAL INFORMATION

1. Description of methods used for collection/generation of data: -
2. Methods for processing the data: -
3. Instrument- or software-specific information needed to interpret the data: -
4. Standards and calibration information, if appropriate: -
5. Environmental/experimental conditions: -
6. Describe any quality-assurance procedures performed on the data: -
7. People involved with sample collection, processing, analysis and/or submission: -

DATA-SPECIFIC INFORMATION FOR: phloretindose.xls

1. Number of variables: 130
2. Number of cases/rows: 32
3. Variable List:

animal, "unique number assigned to each animal"
treatment, "Phloretin dose (dialysis fluid concentration): A: 158 mg/L, B: 50 mg/L, C: 15.8 mg/L, D: 5 mg/L, kontroll: 0 mg/L"
weight, "Body weight in grams before dialysis"
date, "Date of the experiment YYYY-MM-DD"
vin, "Peritoneal dialysis fluid volume instilled in milliliters"
vout, "Peritoneal dialysis fluid volume extracted in milliliters (see manuscript for details)"
uvol, "Total urine volume"
u_fdg_cpm,"18-F activity in urine sample Bq/mL"
p_na_mid, "Plasma sodium concentration after 30 min (mid sample) dialysis in mmol/L"
p_k_mid, "Plasma potassium concentration after 30 min (mid sample) dialysis in mmol/L"
p_cl_mid, "Plasma chloride concentration after 30 min (mid sample) dialysis in mmol/L"
p_ica_mid, "Plasma ionized calcium concentration after 30 min (mid sample) dialysis in mmol/L"
p_tco2_mid, "Plasma total carbon dioxide concentration after 30 min (mid sample) dialysis in mmol/L"
p_glu_mid, "Plasma glucose concentration after 30 min (mid sample) dialysis in mmol/L"
p_urea_mid, "Plasma urea concentration after 30 min (mid sample) dialysis in mmol/L"
p_crea_mid, "Plasma creatinine concentration after 30 min (mid sample) dialysis in mmol/L"
map_before, "Mean arterial pressure before dialysis in mmol/L"
hr_before, "Heart rate before dialysis in mmol/L"
map_after, "Mean arterial pressure before dialysis in mmol/L"
hr_after, "Heart rate before dialysis in mmol/L"
n_p_samples, "Number of blood samples obtained during dialysis"
pt1, "Time point for blood sample #1 in minutes post start of dialysis"
pt2, "Time point for blood sample #2 in minutes post start of dialysis"
pt3, "Time point for blood sample #3 in minutes post start of dialysis"
pt4, "Time point for blood sample #4 in minutes post start of dialysis"
pt5, "Time point for blood sample #5 in minutes post start of dialysis"
hb_mid, "Blood hemoglobin concentration 30 min (mid sample) dialysis in g/L"
hct_mid, "Blood hematocrit 30 min (mid sample) dialysis"
p_fdg_1, "Plasma 18F activity (blood sample #1) in Bq/mL"
p_fdg_2, "Plasma 18F activity (blood sample #2) in Bq/mL"
p_fdg_3, "Plasma 18F activity (blood sample #3) in Bq/mL"
p_fdg_4, "Plasma 18F activity (blood sample #4) in Bq/mL"
p_fdg_5, "Plasma 18F activity (blood sample #5) in Bq/mL"
n_d_samples, "Number of dialysate samples obtained during dialysis"
d_sv_1, "Sampling volume for dialysate sample #1 in milliliters"
d_sv_2, "Sampling volume for dialysate sample #2 in milliliters"
d_sv_3, "Sampling volume for dialysate sample #3 in milliliters"
d_sv_4, "Sampling volume for dialysate sample #4 in milliliters"
d_sv_5, "Sampling volume for dialysate sample #5 in milliliters"
d_sv_6, "Sampling volume for dialysate sample #6 in milliliters"
d_sv_7, "Sampling volume for dialysate sample #7 in milliliters"
d_sv_8, "Sampling volume for dialysate sample #8 in milliliters"
d_fdg_1, "18F activity in dialysate sample #1 in Bq/mL"
d_fdg_2, "18F activity in dialysate sample #2 in Bq/mL"
d_fdg_3, "18F activity in dialysate sample #3 in Bq/mL"
d_fdg_4, "18F activity in dialysate sample #4 in Bq/mL"
d_fdg_5, "18F activity in dialysate sample #5 in Bq/mL"
d_fdg_6, "18F activity in dialysate sample #6 in Bq/mL"
d_fdg_7_1, "18F activity in dialysate sample #7 in Bq/mL"
d_fdg_7_2, "18F activity in dialysate sample #8 in Bq/mL"
d_glu_7_1, "Measured glucose concentration in dialysate sample #7 in mmol/L"
d_glu_7_2, "Measured glucose concentration in dialysate sample #8 in mmol/L"
d_glu_7_3, "Measured glucose concentration in dialysate sample #8 (double) in mmol/L"
d_na_0, "Sodium concentration in fresh dialysis fluid (before instillation) in mmol/L"
d_na_1, "Measured glucose concentration in dialysate sample #1 in mmol/L"
d_na_2, "Measured glucose concentration in dialysate sample #2 in mmol/L"
d_na_3, "Measured glucose concentration in dialysate sample #3 in mmol/L"
d_na_4, "Measured glucose concentration in dialysate sample #4 in mmol/L"
d_na_5, "Measured glucose concentration in dialysate sample #5 in mmol/L"
d_na_6, "Measured glucose concentration in dialysate sample #6 in mmol/L"
d_na_7, "Measured glucose concentration in dialysate sample #7 in mmol/L"
d_k_0, "Potassium concentration in fresh dialysis fluid (before instillation) in mmol/L"
d_k_1, "Measured potassium concentration in dialysate sample #1 in mmol/L"
d_k_2, "Measured potassium concentration in dialysate sample #2 in mmol/L"
d_k_3, "Measured potassium concentration in dialysate sample #3 in mmol/L"
d_k_4, "Measured potassium concentration in dialysate sample #4 in mmol/L"
d_k_5, "Measured potassium concentration in dialysate sample #5 in mmol/L"
d_k_6, "Measured potassium concentration in dialysate sample #6 in mmol/L"
d_k_7, "Measured potassium concentration in dialysate sample #7 in mmol/L"
d_cl_0, "Chloride concentration in fresh dialysis fluid (before instillation) in mmol/L"
d_cl_1, "Measured chloride concentration in dialysate sample #1 in mmol/L"
d_cl_2, "Measured chloride concentration in dialysate sample #2 in mmol/L"
d_cl_3, "Measured chloride concentration in dialysate sample #3 in mmol/L"
d_cl_4, "Measured chloride concentration in dialysate sample #4 in mmol/L"
d_cl_5, "Measured chloride concentration in dialysate sample #5 in mmol/L"
d_cl_6, "Measured chloride concentration in dialysate sample #6 in mmol/L"
d_cl_7, "Measured chloride concentration in dialysate sample #7 in mmol/L"
d_ica_0, "Ionized calcium concentration in fresh dialysis fluid (before instillation) in mmol/L"
d_ica_1, "Measured ionized calcium concentration in dialysate sample #1 in mmol/L"
d_ica_2, "Measured ionized calcium concentration in dialysate sample #2 in mmol/L"
d_ica_3, "Measured ionized calcium concentration in dialysate sample #3 in mmol/L"
d_ica_4, "Measured ionized calcium concentration in dialysate sample #4 in mmol/L"
d_ica_5, "Measured ionized calcium concentration in dialysate sample #5 in mmol/L"
d_ica_6, "Measured ionized calcium concentration in dialysate sample #6 in mmol/L"
d_ica_7, "Measured ionized calcium concentration in dialysate sample #7 in mmol/L"
d_tco2_0, "Total carbon dioxide concentration in fresh dialysis fluid (before instillation) in mmol/L"
d_tco2_1, "Measured total carbon dioxide concentration in dialysate sample #1 in mmol/L"
d_tco2_2, "Measured total carbon dioxide concentration in dialysate sample #1 in mmol/L"
d_tco2_3, "Measured total carbon dioxide concentration in dialysate sample #1 in mmol/L"
d_tco2_4, "Measured total carbon dioxide concentration in dialysate sample #1 in mmol/L"
d_tco2_5, "Measured total carbon dioxide concentration in dialysate sample #1 in mmol/L"
d_tco2_6, "Measured total carbon dioxide concentration in dialysate sample #1 in mmol/L"
d_tco2_7, "Measured total carbon dioxide concentration in dialysate sample #1 in mmol/L"
d_urea_1, "Measured urea concentration in dialysate sample #1 in mmol/L"
d_urea_2, "Measured urea concentration in dialysate sample #2 in mmol/L"
d_urea_3, "Measured urea concentration in dialysate sample #3 in mmol/L"
d_urea_4, "Measured urea concentration in dialysate sample #4 in mmol/L"
d_urea_5, "Measured urea concentration in dialysate sample #5 in mmol/L"
d_urea_6, "Measured urea concentration in dialysate sample #6 in mmol/L"
d_urea_7, "Measured urea concentration in dialysate sample #7 in mmol/L"
d_crea_0, "Measured creatinine concentration in fresh dialysis fluid (before instillation) in μmol/L"
d_crea_1, "Measured creatinine concentration in dialysate sample #1 in μmol/L"
d_crea_2, "Measured creatinine concentration in dialysate sample #2 in μmol/L"
d_crea_3, "Measured creatinine concentration in dialysate sample #3 in μmol/L"
d_crea_4, "Measured creatinine concentration in dialysate sample #4 in μmol/L"
d_crea_5, "Measured creatinine concentration in dialysate sample #5 in μmol/L"
d_crea_6, "Measured creatinine concentration in dialysate sample #6 in μmol/L"
d_crea_7, "Measured creatinine concentration in dialysate sample #7 in μmol/L"
dt1, "Time point for dialysate sample #1 in minutes post start of dialysis"
dt2, "Time point for dialysate sample #2 in minutes post start of dialysis"
dt3, "Time point for dialysate sample #3 in minutes post start of dialysis"
dt4, "Time point for dialysate sample #4 in minutes post start of dialysis"
dt5, "Time point for dialysate sample #5 in minutes post start of dialysis"
dt6, "Time point for dialysate sample #6 in minutes post start of dialysis"
dt7, "Time point for dialysate sample #7 in minutes post start of dialysis (#8 is same as #7)"
d_osm_1, "Dialysate osmolarity for sample #1 in mOsm/L"
d_osm_7, "Dialysate osmolarity for sample #7 in mOsm/L"

1. Missing data codes: NA
2. Specialized formats or other abbreviations used: -