iValiD-TB: A fully characterized Mycobacterium tuberculosis dataset for antimicrobial resistance bioinformatics workflow validations

Lapierre, Pascal1 ; Shea, Joe1 ; Murphy, Shannon2 ; Kohlerschmidt, Donna1 ; Dickinson, Michelle1 ; Musser, Kimberlee1 ; Escuyer, Vincent1 ; Smith, Carol1

Research facility: Wadsworth Center

Published May 08, 2024 on Dryad. https://doi.org/10.5061/dryad.4j0zpc8m8

Data files

May 08, 2024 version files 1.79 MB

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README.md

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Abstract

For clinical assay validations, well-characterized samples are essential for assessing methodology sensitivity and specificity. To support the community in the development of clinical next-generation sequencing assays for Mycobacterium tuberculosis, we released a comprehensive dataset of 50 whole genome sequences from characterized strains, complete with drug susceptibility and mutation profiles.