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Data for: Fabrication and characterization of antibacterial coatings using an amphoteric condensed tannin,Tanfloc

Data files

Nov 29, 2023 version files 300.32 KB

Abstract

This dataset presents comprehensive information on the development and characterization of antibacterial polyelectrolyte multilayer (PEM) coatings incorporating tanfloc, a plant-derived condensed tannin polymer with inherent antimicrobial properties. The dataset encompasses experimental data related to the fabrication of PEMs using tanfloc as either a polyanion or a polycation, expanding the versatility of this amphoteric polymer in PEM coatings. Typically, PEMs are formed by combining a polycation and a polyanion with complementary ionic groups. However, the unique amphoteric nature of tanfloc allows for the creation of PEMs utilizing only one of its functional groups, leaving the other functional group available for imparting antibacterial activity.

The dataset includes details on the assembly of tanfloc-containing PEMs employing various counter-polyelectrolytes, including three poly-anionic glycosaminoglycans with varying charge densities, as well as the polycations N,N,N-trimethyl chitosan and polyethylenimine. The layer-by-layer assembly of PEMs is monitored using in situ Fourier-transform surface plasmon resonance (FT-SPR), confirming stable layer-by-layer construction. Surface chemistry is assessed through X-ray photoelectron spectroscopy (XPS).

Furthermore, this dataset provides insights into the biocompatibility of tanfloc-containing PEMs, demonstrating their support for mammalian cells. Most notably, the dataset includes extensive data on the antiadhesive and antibacterial properties of these coatings against common implant-associated pathogens, such as Staphylococcus aureus and Pseudomonas aeruginosa. The antibacterial effects observed are attributed to electrostatic interactions and the polyphenolic nature of tanfloc.